Jaitly, N., Brubaker, M.A., Rubinstein, J.L. and Lilien, R.H. A Bayesian Method for 3-D Macromolecular Structure Inference using Class Average Images from Single Particle Electron Microscopy, Bioinformatics, 26(19):2406-15 (2010). Pubmed Link

We provide a Linux package built with glibc4.1 on Ubuntu 9.1 and a Windows package build on Windows Vista using Microsoft Visual Studio 2008. See Instructions on how to run the program. Note: The OS X distribution contains a precompiled binary for OS X 10.6.

CryoBayes is distributed under the GNU Lesser General Public License.

Datasets and results from the application of our program to a synthetic dataset, to ATP Synthase, and to GroEL are also available for download:

• Synthetic Dataset (zip,tar.gz): Model of synthetic object and its projections obtained from John Rubinstein.
• ATP Synthase (zip,tar.gz): Class Averages were obtained from John Rubinstein.
• GroEL (zip,tar.gz): The raw GroEL dataset was obtained from the National Resource for Automated Molecular Microscopy. Class Averages were generated using XMIPP program mlalign_2d.